We aim to map the full landscape of small molecules in our bodies, and understand how food, microbes, and the environment shape them.
我们致力于解析人体内小分子的完整图谱，并理解食物、微生物与环境如何塑造它们。
Mass spectrometryMetabolomics & ExposomicsBioinformaticsData miningMachine learning
Latest News
May 10, 2026
Openings for students and postdocs
Prospective lab members interested in metabolomics, bioinformatics, computational chemistry, and data science are encouraged to get in touch.
Featured Lab Papers
bioRxiv, in revision at Nature, 2026
Shipei Xing*, Abubaker Patan, Julius Agongo, Harsha Gouda, Vincent Charron-Lamoureux, Yasin El Abiead, Zhewen Hu, Haoqi Nina Zhao, Ipsita Mohanty, Jasmine Zemlin, Wilhan Donizete Gonçalves Nunes, Lindsey A. Burnett, Mingxun Wang, Dionicio Siegel, Pieter C. Dorrestein*
Read paper
Nature Methods, 2023
Shipei Xing, Sam Shen, Banghua Xu, Xiaoxiao Li, Tao Huan*
Read paper
Now Recruiting
We welcome motivated students and researchers from all backgrounds to join us in exploring the metabolome and xenobiotic metabolism. Applicants with diverse experiences, perspectives, and skill sets are encouraged to apply.
Image generated by AI
Research directions
When you eat an apple, which molecules become you, which fuel you, which feed your microbes, and which leave you?
To answer this question, our lab links computational innovation, open-data mining, and experimental metabolomics to annotate and discover small molecules, with a focus on understanding xenobiotic metabolism. Together, these directions turn complex mass spectrometry data into reusable biochemical insight.
We develop algorithms and workflows that make complex mass spectrometry data more interpretable, scalable, and useful for molecular discovery and downstream biochemical interpretation.
We turn public metabolomics repositories into reusable discovery resources by reanalyzing spectra, and linking them to new biological and environmental questions.
We use metabolomics and informatics to understand how microbes transform xenobiotics and shape molecular exposures.
